So far, the study is in early stages and yet to be confirmed by peer review. Same as the easier side effects for other vaccines. Interestingly, researchers also believe it could be developed to treat other conditions like cancer. The ultra-low dose saRNA technology has the potential to protect against a variety of other infectious diseases, such as rabies and Ebola. SaRNA COVID vaccines can be given in smaller amounts, so can cover larger populations with less vaccine. Are saRNA COVID vaccines different to mRNA ones? This genetic information holds instructions to make a protein found on the outside of the coronavirus, called the spike protein.
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The technology uses genetic code called self-amplifying RNA (saRNA). The immune system identifies the spike as a huge danger, then creates antibodies to counteract it. The saRNA strategy is to send spike protein making instructions to the immune system, which then creates the spike found in the virus. Self-amplifying RNA has a similar technology to messenger RNA vaccines, like Pfizer and Moderna. They found that 87% of the group created a strong antibody response when given saRNA.
In this study, they looked at the impact of a different vaccine tech in 192 people, aged between 18-45. Currently, the world has unequal access to vaccines, meaning that new and powerful variants will continue to mutate until all countries are majority-double dosed. © Ahasoft While mRNA is now well-connected to Pfizer or Moderna, saRNA is a more obscure, early-stage vaccine technology – now, scientists in the UK have data suggesting that saRNA COVID vaccines could work well for most peopleĪ team of researchers at Imperial College London are trying to establish how well saRNA vaccines can work against COVID – especially as booster shots over the next ten years.
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